Ann’s deception was found out and Tiffany’s dad dumped her, and she hasn’t been back since (plus every one of the main characters are wise to her act now, so she has no more marks to swindle.)
I doubt G&K will ever allow her to have a relationship again, and definitely not a one-night-stand. The most she’ll get are bad first dates played for laughs. Notice how she’s already given up on dating apps altogether after a single bad experience (and we never did find out why that guy left so quickly.)
Nancy kicking Ann out had the unintended side effect of making TJ officially Dead To Me, since it showed that he HAD in fact been witness to Ann’s abuse of his employee and hadn’t done anything about it.
The problem was that before she broke up with Quill, her defining attribute was “boy-crazy.” But once Greg realized that she was now old enough to be sexually active (and that readers might start to wonder why she never actually engaged in the activity she was so obsessed about), he removed that part of her character altogether but didn’t replace it with anything, leaving her personality as an empty void.
Then you must be pretty annoyed that Luann seemed to shoot it down in the very next panel.