There was a big Nate, strip a long while ago when Nate gets hit in the face with a basketball and his lips swells up on school picture day, and the school picture guy gets mad at him because he stopped that he got a collagen injection… He seems to have changed his mood towards it…
That is one strong baby, but however, we do see her pull a wagon full of HEAVYWEIGHTS at 70 MPH later in the comic series… and THAT’S PRETTY DARN IMPRESSIVE!
At least Nate knows that the only way for them to beat him is to bring in outside tools. (e.g. Egg salad sandwiches, Cats, etc.)