Doonesbury by Garry Trudeau for July 22, 1977
Transcript:
Duke: Nephew, now, be reasonable... Zonker: No, Duke! I don't want to have anything to do with your pit farm! There's just no way I'm going to help you finance an operation that preys on the hopes of desperately ill people! Duke: *sigh* I knew it... I knew it would happenn... Zonker: What, Duke? Duke: It's the F.D.A, isn't it? They got to you, right? Zonker; I'm not sure, Duke... they were so big... it was dark...
And look at what Zonker and Zipper do for a living now! ;)